chylomicrons and low density lipoproteins. it occurs in plasma as two main isoforms, apob- and apob- : the former is synthesized exclusively in the gut and the latter in the liver. the intestinal and the hepatic forms of apob are encoded by a single gene from a single, very long mrna. the two isoforms...
the chylomicron, binds to a specific receptor on liver cells and peripheral cells. apoe is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. the apoe gene is mapped to chromosome in a cluster with apoc and apoc . defects in apolipoprotein e result in familial dysbetalipoproteinemia...
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