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non-specific activation of t-cells, resulting in polyclonal t-cell activation and massive cytokine release. tolerogen – a substance that invokes a specific immune non-responsiveness due to its molecular form . if its molecular form is changed, a tolerogen can become an immunogen. immunoglobulin -binding

protein – proteins such as protein a , protein g , and protein l that are capable of binding to antibodies at positions outside of the antigen-binding site. while antigens are the "target" of antibodies, immunoglobulin-binding proteins "attack" antibodies. t-dependent antigen – antigens that require...

https://en.wikipedia.org/wiki/Antigens

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