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several mistakes in their data collection that led to errors in the meta-analysis. in table of their letter, they indicated the outcome of guan et al. study to be 'admission to icu, mechanical ventilation, death', however, they used the data of 'severe disease' in the study. according to the guan et al. paper
, the number of patients having composite outcome should be , and for patients not having a composite outcome should be . however, lippi and henry used and , respectively, in their paper. this is the most serious mistake because the guan et al. study contributes to most of the cases in the meta-analysis...
http://www.tobaccoinduceddiseases.org/Active-smoking-is-associated-with-severity-of-coronavirus-ndisease-2019-COVID-19,121915,0,2.html
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